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Management of Phentermine Withdrawal Effects

Management of Phentermine Withdrawal Effects

Phentermine is recommended for a short period. It is recommended to stop its use gradually rather than stopping it at once because it produces withdrawal symptoms which can be avoided by its taper use and weight can be maintained easily. Phentermine’s effect starts gradually and decreases towards the end of therapy that’s why its absence does not harm weight-loss procedure. Weight loss journey can be continued with comprehensive lifestyle changes which include calorie-restricted diet, greater physical activity, behavioral policies, and nutrient-dense foods and which gives long term weight loss.

How long does phentermine stay in your system?

Phentermine stays in the body for a period that starts with its administration and ends with excretion of its last fragment. It comes into circulation through the Gastrointestinal tract in almost four hours after its administration. It remains in blood circulation and then the liver takes it for metabolism. Tests show that it can be detected in blood for 24 hours. Its half-life is 25 hour and it requires five to six half-life for its complete removal from the body. It can be detected for three to four days in urine which means that it stays in the body for three to four days.

Purchase of phentermine

Phentermine is available very easily at local pharmacies and also online. It depends on the consumer’s choice to select the method, which suits him. Purchase from local pharmacy gives the advantage of instant use at urgent basis. Online orders take time for delivering it but this will be helpful for users at distant places, who cannot visit the market due to a shortage of time or absence of drugs at their local pharmacy.

Phentermine 37.5 mg

Phentermine 37.5 mg is the highest dose which can be given in the form of an extended-release capsule and can be easily purchased from local pharmacies and also from official websites. People are usually recommended to take it once per day.

Price of phentermine

Phentermine belongs to a stimulant class. It is not expensive and easily available. The price of the drug depends on many factors which gives you a range of prices in the market. The source of the drug and quality of excipients define its price. With us, you can get phentermine for $6.99-7.99.

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Diet Plan To Follow While Using Phentermine

Diet Plan To Follow While Using Phentermine

The diet plan is followed by phentermine to reduce weight. A calorie-restricted diet is taken which must include all necessary elements for the body. Food with low calories is best for use as they give fewer calories with satiety. Regular exercise is needed that’s why it must include a small portion of a protein which gives strength to muscle mass. Try to minimize the daily take of carbohydrates as much as possible because carbohydrates give high calories. Use vegetables which give fewer calories while the use of meat and dairy product gives high energy which is stored in the form of fat.

What I can take with phentermine to make it work better?

Phentermine effect can be enhanced by different measures. It may be a drug or any food item which makes it weight loss response more effective. Topiramate, an anticonvulsant, co-administered with phentermine helps you to reduce more weight. Taking phentermine with alkaline food help it to stay longer in the body and increase its exposure time which gives more effect.

What is the highest dose of phentermine?

Drug effectiveness is obtained by using its accurate dose.  When it starts giving a response, the drug level is called a minimum effective dose and the highest effective dose is the maximum concentration at which it gives a maximum response. For phentermine, 37.5 mg is the maximum daily dose. A dose greater than 37.5 mg can cause a toxic effect. Taking a higher toxic dose may become a lethal dose.

Where to buy phentermine online that is real in quality?

Online purchase of phentermine is very risky if you purchase it from any website without confirmation of license and legal procedure. Purchase directly from manufacture by contacting at their official website assure you to get real phentermine with greater effectiveness. Distributors of drugs also work officially online and deal with orders legally. Websites working under rules and are licensed provides you actual drugs.

How to get phentermine work again?

Phentermine loses its effect when it is used for a longer time. The use of greater doses to get high effectiveness develops tolerance. To overcome this problem, physicians ask patients to quit therapy. Fractions of the drug started to eliminate from the body with time. After a certain period drug leaves body and receptors become available for new binding. The physician recommends taking phentermine again to get its help in weight loss. Phentermine starts binding with receptors and produces results.

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Role Of Phentermine In Reducing Obesity

Role Of Phentermine In Reducing Obesity

Obese patients who are suffering from other problems like high cholesterol level, high blood pressure, diabetes needs to reduce weight with speed. Special diet chart with exercises helps in this way but it needs aid which makes this easy. Patients’ body mass index is calculated and if this value is higher than 27 kg/m2 or sometimes this value is taken as 30 kg/m2, then physicians prescribe phentermine. Phentermine is a famous weight lowering medicine which works by appetite suppression. It gives satiety and helps to control calorie intake which helps to get rid of problematic weight.  Initially, it helps to reduce 5% of initial body weight which may increase to 10%.

How Long Phentermine Stay In Blood

Phentermine after absorption comes directly into the blood. It starts producing an effect as the concentration rises to peak level. Tests are performed to check phentermine presence in blood and results show that it appears for only 24 hours after administration. Its half-life is 24 hours and it requires five to six half-life for its complete metabolism.

Time Phentermine takes to start its actions

The physician prescribes phentermine to reduce body weight. It is used in the form of tablets and extended-release capsules. After administration of dosage form, it takes almost three to four hours for the drug to reach its maximum concentration. The drug effect is related to drug concentration in the blood. Phentermine begins to give its stimulant effect in almost 3 hours.

Causes of the Phentermine’s failure to produce the response

Phentermine’s use is restricted to a short period. It is a controlled substance that must be used according to prescription because this can be abused. A higher dose than the recommended one and then taking it for a longer time may result in loss of response.  This phenomenon is called tolerance. In this condition, the body stops responding against drug use and it occurs due to the saturation of receptors. Repeated exposure to phentermine also causes tolerance.

Place online order for phentermine

It is very easy to buy phentermine online. Different websites are working which are involved in online dealing with phentermine. Phentermine manufacturers are now dealing directly with their consumers through their official websites. Ordering from any other website dealing with phentermine must be checked whether it is licensed or not. The drug must be ordered from a licensed website. Ordering directly from manufacturers is very safe as they are performing all procedures according to rules and regulations.

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How Does Phentermine Cause Reduction In Weight?

How Does Phentermine Cause Reduction In Weight

Phentermine helps to increase the rate of weight loss. Diet chart is selected according to the patient daily energy requirement. This calorie-restricted diet accompanied by the regular exercise reduces weight. A lot of exercises not only reduces weight but also strengthen muscle mass. Exercise helps to increase metabolism thereby reducing fat deposition. Anti-obesity drugs cannot be administered due to severe side effects. Other drugs can also b co-administered to facilitate this journey e.g topiramate of anticonvulsant class can be given which reduces weight.

Other factors which can hinder its performance

Physicians prescribe phentermine when an overweight patient is at risk to develop other serious problems. It becomes necessary to get rid of this extra weight as soon as possible. Phentermine helps in reducing exogenous obesity. This obesity is because of unhealthy diet, sedentary lifestyle and consumption of high-calorie food products which makes the body to store extra calories in the form of fat. Phentermine works by controlling appetite. If phentermine does not work in lowering weight it means that hormones are involved in this weight gain. This endogenous obesity needs hormonal treatment.

Phentermine’s purchase

Phentermine can be purchased from any nearby pharmacy. As phentermine comes under controlled substances, it needs a physician’s authorization to get it easily from any local pharmacy. Advancements in technology make it possible to purchase phentermine online. Online purchase removes the hurdle of prescription and provides medicine on demand but they do not deny the importance of physician’s referral for medicine.

Buy phentermine online

Official websites are dealing with online buying of phentermine. Manufacturers of phentermine tablets and capsules run their websites to help their consumers to get medicine at the doorstep. It also helps to get a real drug from a manufacturer who is famous for high-efficiency products. Buying phentermine from brands that provide high-efficiency products. It helps you to get maximum weight loss while on phentermine.

Online order of phentermine

The patient should go for an online order of phentermine after the physician’s recommendation. Find out the official website which is licensed and deals legally with drugs. Select the prescribed dosage form of the required strength. Some websites demand a copy of prescription through fax. After completing these steps they get confirmation of the patient’s age. Then select a method of payment and provide the shipping address. In a given time frame they will deliver it.

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Legally Purchasing The Real Phentermine Online

Legally Purchasing The Real Phentermine Online

Phentermine helps to reduce weight with increased learning capacity. Online availability of phentermine has made it easy to buy it cost-effectively. Websites dealing with drug purchases are licensed making this whole process to be completed according to rules. Manufacturers of phentermine tablets and capsules also invite their customers through their official websites. These official websites provide real drugs without any ambiguity. Online orders are time-saving, convenient and economical. Stockists of drugs offer different deals to make phentermine purchase cost-effective for online users.

Buy phentermine from brands of your choice

Online availability helps you to get the most effective brand. It allows you the opportunity to get medicines from any international brands which are available online. These official websites provide a user guide that gives complete information regarding phentermine use. Official websites dealing with medicine’s online business also provide a list of stockiest of international brands so you can select one who can deliver medicine instantly. These websites assure that these stockists are licensed holders and deal legally with medicines.

Phentermine purchase without prescription

Phentermine online buying helps to get it without a prescription. It comes under controlled substances that require a physician’s approval for use. The patient should be clear about phentermine’s use and duration of therapy. The age of the person is verified before order placement. People of age above 18 years can place their orders online and re-ordering through the same official website confirms that from how much time you are using phentermine. Websites offering phentermine purchase does not invite you to take this drug but guide you to order this after physician’s prescription. Phentermine’s abuse is possible which causes addiction and dependence. This problem comes in online purchasing that need special attention to avoid drug abuse.

Online prescription

New ways of interactions make it easy to get prescriptions at home. Physicians are providing their services online to facilitate their patients. It helps the patient to contact their physician anytime and get a solution to their queries. Physicians after taking a complete history of patients prescribe phentermine and this prescription can be used in placing an online order.

Buy phentermine over the counter

Phentermine which is purchased from a local pharmacy needs a prescription. Over the counter, medicines don’t require prescription and consumers can buy them easily while prescription drugs need a valid prescription. Phentermine comes under the category of prescription drugs.

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Effects After Cessation of Phentermine Therapy

Phentermine should be taken according to prescription and should be stopped as recommended because, in the case of neglect, all possible side effects and withdrawal symptoms appear. Weight loss speed slows down but not too much. This is due to the phentermine effect which is greater at the start of therapy and then it slows down so the end of therapy does not give drastic change. Calorie restricted diet and regular exercise are recommended through the weight loss journey which keeps it on track.

Maintain weight after phentermine:

Diet is the actual game-changer in the weight loss program. Dietitian constructs diet chart to take only the required calories. Calorie intake is controlled with proper strength-giving exercises. Portion control diet is the main concern rather than skipping a meal because it can harm your plan to maintain weight.

Phentermine’s snorting:

Phentermine is a stimulant of schedule 4 which may cause addiction if used for a long period. Its abuse is possible by crushing, snorting or taking a higher dose of the drug. Phentermine’s snorting is very risky and produces serious effects. Snorting gives the patient a quick high response related to satisfaction and satiety. This drug abuse can b limited by taking the drug as prescribed for a specified period.

Phentermine gives a false positive screen:

When the urinalysis test is performed, phentermine gives a false-positive screen for amphetamine. This is due to its similarity with the amphetamine structure. This similarity can fail you in a drug test. To clear this ambiguity a confirmatory test is performed to assure that it was phentermine. This test also helps in differentiating it from amphetamine and methamphetamine

Phentermine shows up on a drug test:

For a patient taking 37.5 mg phentermine, time to appear in drug test is different for urine, blood, and hair. Duration for an appearance on a drug screen while performing urinalysis is one to four days. After administration, phentermine can be detected in blood up to 24 hours and in hair tests up to one month.

Blue specks on phentermine tablets:

Phentermine tablets available in the online market have blue specks on the white color base. Active in these tablets is phentermine which is a white color powder while other ingredients are anhydrous lactose, microcrystalline cellulose, sucrose, pregelatinized starch, microcrystalline cellulose, corn starch, magnesium stearate and FD&C Blue #1. This FD&C Blue #1 gives color and blue specks appear on the white base.

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Difference Between Adipex-P and Phentermine

Phentermine is a generic which is sold under different brand names. Adipex is one of these brands which contain phentermine as an active pharmaceutical ingredient. Adipex contains it in form of phentermine hydrochloride. It contains 37.5 mg phentermine hydrochloride which is equivalent to a 30 mg phentermine base. Adipex-P comes in tablet and capsule form and gives extended-release effects after once-daily administration.

Belviq compared to phentermine.

Belviq can be compared with phentermine as both have a stimulant effect. Lorcaserin is sold under the brand name Belviq. Belviq gives stimulant effect. It is a serotonin 2C receptor agonist and increases serotonin secretions in the brain.  When its level rises, it promotes satiety and minimizes food consumption thus it helps in the regulation of appetite. Phentermine increases dopamine, serotonin and norepinephrine level by minimizing their uptake and inhibiting monoamine oxidase enzyme. It is used for a short time and gives the same diet control effect.

Comparison between tenuate and phentermine

Phentermine & Tenuate both weight loss drugs are FDA approved. They are anorexiants and have stimulant action and gives a similar impact on the body. The theoretical comparison does not prove which one is better. But when studies are carried out to compare their effectiveness then greater weight loss is observed in people who use phentermine. In clinical practice, phentermine is widely used than Tenuate dospan.

Phentermine in qysmia:

A combination of medicines is used to get more effective results. FDA approves Qysmia in 2012 in the treatment of obesity. Qysmia is a combination of two drugs, phentermine, and topiramate. Indications for Qysmia are the same as phentermine and gives a highly effective weight loss effect. Extended-release capsules of Qysmia are available in four strengths: Qysmia 3.75 mg/23 mg, Qysmia 7.5 mg/46 mg, Qysmia 11.25 mg/ 69 mg, and Qysmia 15mg/92mg. The ratio of phentermine to topiramate is 1: 6.13.

Topamax and phentermine use in weight loss:

Topamax is the brand name of topiramate. Topiramate is an anticonvulsant and used in the treatment of seizures in epilepsy and the prevention of migraine headaches. It reduces the weight of patients as its most common side effect. This side effect can be used as an adjuvant in weight loss by coadministration of topiramate with phentermine. Physicians prescribe specified strengths of extended-release of phentermine and topiramate that should be taken every day at the same time. Different combinations are also available in the market.

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How Does Effectiveness of Phentermine Reduce

How Does Effectiveness of Phentermine Reduce

Generally, phentermine gives better results at the start of therapy which reduces afterward. If it gives unusual results of diminished appetite suppression with the same dose, tolerance is the main reason. This tolerance makes phentermine less responsive. Taking a higher dose than recommended one will not get effectiveness back but intoxication.

Reasons for tolerance toward phentermine

Tolerance is nothing but the reduced response of receptors as the body adapts to the drug. Tolerance is due to different reasons. Extending the course duration of phentermine for long time results in the tolerance of the drug. That’s why it is recommended to take this controlled drug for a short duration. Repeated use is also a reason. Doubling the dose to get more effect saturates the receptors and it ultimately shows less response.

Measures needed to take after tolerance buildup

When phentermine stops working and does not aid in weight loss due to tolerance, it is recommended to stop using it completely. Increasing its dose or duration will not help but produces serious life-threatening side effects. the physician decides whether to stop therapy suddenly or gradually. It is better to quit phentermine therapy gradually to avoid withdrawal symptoms.

Regaining of the phentermine’s effectiveness

Tapering methods are adopted to decrease tolerance toward phentermine. Regular exercise and eating food that acidifies urine will help in the excretion of phentermine. Phentermine has 25 hours half-life means it needs five to six half-lives for its complete elimination. Traces of drug leave the body with the passage of time and receptors becomes free to perform their function actively. The doctor will instruct you to restart phentermine after a certain time to get its same effects.

Duration of the withdrawal symptoms

Withdrawal symptoms like anxiety, depression, and hyperactivity appear when phentermine therapy is abruptly stopped. The duration of these symptoms is linked with therapy time. The cessation of a drug after long time therapy produces strong withdrawal symptoms which last longer.

 

Reason for withdrawal symptoms

Phentermine works by stimulating the central nervous system.  Neurons secrete more neurotransmitters of a class called catecholamines, which are involved in halting hunger signaling and increasing signaling for satiety. The brain becomes relax as it produces a less amount of neurotransmitters on its own and depends on stimulation from phentermine. When therapy is stopped suddenly withdrawal symptoms are produced as the brain is not ready to handle the situation and to maintain the required level of neurotransmitters.

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How Long Does Phentermine Stay & Work In The Body

How Long Does Phentermine Stay & Work In The Body

Phentermine works as an adjuvant in a weight loss regimen. It reduces exogenous obesity by staying in the body for days after administration. While using phentermine, the next dose is taken before the complete elimination of the drug. After the last dose, it takes three to five days for complete removal with normal metabolism. Metabolic rate and body type define phentermine stay in the patient’s bloodstream. Fast metabolism and thin body type make the stay of phentermine shorter because they fasten phentermine movement through the digestive system.

Toxicity of phentermine’s overdose:

Phentermine is a controlled drug to suppress appetite. Physicians prescribe individualized doses to get maximum results with the lowest effective dose. The maximum dose of phentermine is 37.5 mg. This is the highest effective dose. Drug effectiveness ranges between lowest to highest effective dose but causes serious side effects above the highest dose, termed as a toxic dose. In the case of phentermine abuse for longer time or use of larger dose to get the effect when tolerance build-up, chronic intoxication results in severe side effects.

Phentermine therapy for a short time:

Phentermine is a drug of Schedule IV, a classification which classifies drugs depending on their possibility of abused or overdose. Class I has a higher tendency and it decreases in the next classes gradually. Phentermine shows a low potential for abuse. It can cause dependence by working as CNS stimulant and tolerance may occur which reduces its effectiveness. So phentermine’s use must be viewed carefully and that’s why it is prescribed for almost 12 weeks and the least effective dose should be selected to reduce the chances of overdosage.

Gradual cessation of phentermine therapy:

Phentermine is a sympathomimetic drug. It is used according to prescription to avoid overdose or misuse of the drug. After completion of therapy, it is recommended to gradually decrease the dose. Sudden termination of dose may produce withdrawal effects. These effects include depression, lethargy, fatigue, insomnia and personality change.

Weight loss  and weight maintenance after phentermine:

It is not difficult to reduce weight after cessation of phentermine therapy. Phentermine is an aid that helps in weight loss with a calorie control diet and regular exercise. Effectiveness of phentermine is greater at the start of therapy and then it reduces. So ending its use does not abruptly change the weight-loss pathway. It gives speed to fat loss which can easily be controlled with calorie-restricted diet and exercise.

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Phentermine & Food to Eat Along While Taking It

Phentermine & Food to Eat Along While Taking It

An adequate amount of water is necessary with phentermine otherwise dehydration causes side effects. Phentermine gives the feeling of fullness and this effect is enhanced with protein which takes longer to digest. This makes you feel full faster. Protein also helps to give strength to your muscles during weight loss. Eating healthy fiber, vegetables and fruits give good results as they provide full feeling with low calories and fats. Fruits and vegetables have an alkaline property, which keeps the body at a low alkaline level and maintains pH of urine which helps phentermine to stay in the body for a maximum time and are suitable to take along phentermine.

Foods to avoid with Phentermine:

Avoid acidifying foods with phentermine because they increase its excretion with inhibition of fat burning. So avoid coffee, sugar, soda white flour items and ice cream. Alcohols affect liver function to burn fats. Carbohydrates rich diet and sugar provide fructose; need to be metabolized by the liver which is converted to fat if not metabolized properly while on phentermine liver is busy for phentermine metabolism.

Time phentermine takes to flush out of the system:

Time, which is taken to eliminate drugs depends on different factors which include dose, duration of use, weight, and age of the patient. Metabolism of the person also affects phentermine excretion. It takes three to five days for a person of average metabolism and weight to remove phentermine out of the body after stopping its use. But it varies with changing factors. Patient with slow metabolism takes more time to flush out phentermine.

Excretion of phentermine out of the system:

Phentermine is a sympathomimetic amine anorectic, reaches peak concentration after three to four hours of administration. After absorption from the gastrointestinal tract, it comes into blood circulation. The Liver converts phentermine into its metabolites. It is reported that about 6% of administered dose goes through metabolism by the liver. The pathway to flush out phentermine is urine. It is excreted in the urine. 70-80% of the administered dose is excreted unchanged.

Phentermine excretion in 24 hours:

Larger intake of water and other fluids helps to eliminate phentermine rapidly. All factors including food items and medications, which make the urine more acidic enhance phentermine excretion.  The patient’s age is related to drug metabolism. An individualized lowest effective dose for phentermine is prescribed to get the required result. In the case of the lowest dose, it takes a shorter period to get out of the body.