Phentermine works as an adjuvant in a weight loss regimen. It reduces exogenous obesity by staying in the body for days after administration. While using phentermine, the next dose is taken before the complete elimination of the drug. After the last dose, it takes three to five days for complete removal with normal metabolism. Metabolic rate and body type define phentermine stay in the patient’s bloodstream. Fast metabolism and thin body type make the stay of phentermine shorter because they fasten phentermine movement through the digestive system.
Toxicity of phentermine’s overdose:
Phentermine is a controlled drug to suppress appetite. Physicians prescribe individualized doses to get maximum results with the lowest effective dose. The maximum dose of phentermine is 37.5 mg. This is the highest effective dose. Drug effectiveness ranges between lowest to highest effective dose but causes serious side effects above the highest dose, termed as a toxic dose. In the case of phentermine abuse for longer time or use of larger dose to get the effect when tolerance build-up, chronic intoxication results in severe side effects.
Phentermine therapy for a short time:
Phentermine is a drug of Schedule IV, a classification which classifies drugs depending on their possibility of abused or overdose. Class I has a higher tendency and it decreases in the next classes gradually. Phentermine shows a low potential for abuse. It can cause dependence by working as CNS stimulant and tolerance may occur which reduces its effectiveness. So phentermine’s use must be viewed carefully and that’s why it is prescribed for almost 12 weeks and the least effective dose should be selected to reduce the chances of overdosage.
Gradual cessation of phentermine therapy:
Phentermine is a sympathomimetic drug. It is used according to prescription to avoid overdose or misuse of the drug. After completion of therapy, it is recommended to gradually decrease the dose. Sudden termination of dose may produce withdrawal effects. These effects include depression, lethargy, fatigue, insomnia and personality change.
Weight loss and weight maintenance after phentermine:
It is not difficult to reduce weight after cessation of phentermine therapy. Phentermine is an aid that helps in weight loss with a calorie control diet and regular exercise. Effectiveness of phentermine is greater at the start of therapy and then it reduces. So ending its use does not abruptly change the weight-loss pathway. It gives speed to fat loss which can easily be controlled with calorie-restricted diet and exercise.
An adequate amount of water is necessary with phentermine otherwise dehydration causes side effects. Phentermine gives the feeling of fullness and this effect is enhanced with protein which takes longer to digest. This makes you feel full faster. Protein also helps to give strength to your muscles during weight loss. Eating healthy fiber, vegetables and fruits give good results as they provide full feeling with low calories and fats. Fruits and vegetables have an alkaline property, which keeps the body at a low alkaline level and maintains pH of urine which helps phentermine to stay in the body for a maximum time and are suitable to take along phentermine.
Foods to avoid with Phentermine:
Avoid acidifying foods with phentermine because they increase its excretion with inhibition of fat burning. So avoid coffee, sugar, soda white flour items and ice cream. Alcohols affect liver function to burn fats. Carbohydrates rich diet and sugar provide fructose; need to be metabolized by the liver which is converted to fat if not metabolized properly while on phentermine liver is busy for phentermine metabolism.
Time phentermine takes to flush out of the system:
Time, which is taken to eliminate drugs depends on different factors which include dose, duration of use, weight, and age of the patient. Metabolism of the person also affects phentermine excretion. It takes three to five days for a person of average metabolism and weight to remove phentermine out of the body after stopping its use. But it varies with changing factors. Patient with slow metabolism takes more time to flush out phentermine.
Excretion of phentermine out of the system:
Phentermine is a sympathomimetic amine anorectic, reaches peak concentration after three to four hours of administration. After absorption from the gastrointestinal tract, it comes into blood circulation. The Liver converts phentermine into its metabolites. It is reported that about 6% of administered dose goes through metabolism by the liver. The pathway to flush out phentermine is urine. It is excreted in the urine. 70-80% of the administered dose is excreted unchanged.
Phentermine excretion in 24 hours:
Larger intake of water and other fluids helps to eliminate phentermine rapidly. All factors including food items and medications, which make the urine more acidic enhance phentermine excretion. The patient’s age is related to drug metabolism. An individualized lowest effective dose for phentermine is prescribed to get the required result. In the case of the lowest dose, it takes a shorter period to get out of the body.
Phentermine is in use for many years and proved itself the most effective and safe medication for obese patients. It is a prescription drug that falls in the controlled drug category. Development in research and technology makes it easy to access different medicines under the regulation of rules. Phentermine is one such drug available online. Before this advancement of technology and easy access to phentermine, this was a prescription drug. But online access makes its availability without the need for a prescription.
How to buy real phentermine online?
Officially licensed websites are available from which you can buy real phentermine online. Direct links are available to connect with actual manufacturers of the medicine, who guarantee to provide the official drug with cost-effectiveness and give you easy access to phentermine. Buying through this method is not only convenient and time-saving but it is also a golden opportunity for people who are too busy to go to the market. They can also use the medicine easily and can have its benefits.
Buying phentermine online is cost-effective
Online medications can be ordered directly from their manufacturers, so they charge less than pharmacies. Stockiest of online medication offers a different discount as they are also a manufacturer of the drug. The chances of savings increase by buying the phentermine online along with the ease of the buying method.
Phentermine is helpful in the reduction of weight
Regular use of phentermine for a defined period helps to reduce weight successfully and shows positive results in a reasonable period. Generally, phentermine is prescribed for 12 weeks with strict time following. The proper use of medicine along with a controlled diet reduces weight effectively. Exercise is also recommended in this period to fasten weight reduction and to strengthen body muscles. The decrease in weight helps an obese person in controlling their anxiety attacks as well.
Positive impact on life
It is an effective medicine in weight loss. Reduction of weight also helps people to feel better about them and it aids them in overcoming their anger, anxiety and mood swings, so along with the physical health, mental health also improves, which makes their approach toward a life more positive and optimistic. It also increases learning capacity due to the regulation of hormones by reducing weight and chances of them showing good performance in their all walks of life increase. Nowadays one can have easy access to phentermine by ordering it online
Improves the social life of people
Obesity results in the deterioration of the social life of the people as well because people become shy and reserved. They do not feel like going to the public gathering. They can develop anxiety which increments in their loss of social life. After using phentermine, they become successful in reducing weight and also feel positive and better about themselves. They become more outgoing and their social life gets back. Because of which, they can make a lot of friends and get to have more exposure to the different aspects of life.
Level of self-confidence also goes up
Loneliness or negative approach toward life because of the mental stress also results in the downfall of one’s self-confidence and self-esteem, which impedes the growth of a person in life. The use of the phentermine results in the reduction of the weight, which also decreases the level of mental stress and one starts getting back his level of self-confidence and self-belief. They get to know that they are capable of fulfilling their goal and they follow the same approach of determination for dealing with the other aspects of their life and become more confident about themselves.
Certain drugs are used to facilitate the weight loss process with regular exercise and calories controlled, well-balanced diet. The most popular drug in this regard is phentermine, used worldwide. It is a drug of anorectics class generally called appetite suppressants. The use of phentermine reduces calorie intake by appetite suppression, which ultimately reduces weight. Its working is linked to its stimulant effect on the central nervous system. Neurons release norepinephrine and dopamine after stimulation and the level of neurotransmitters increases. These neurotransmitters suppress appetite and that’s how phentermine works.
Need to prescribe phentermine:
Physicians prescribe this drug of control category as an aid to weight loss when the patient is obese and has different risk factors like high cholesterol, diabetes or high blood pressure. It becomes necessary to reduce weight on an urgent basis. Body mass index of the patient is calculated and if the calculated value is equal or greater than 27 kg/m2 or 30 kg/m2, phentermine is prescribed. The patient is given a calorie chart to follow with regular exercise.
The maximum daily dose of phentermine:
Physicians prescribe phentermine for obese patients at risk of different medical issues to reduce weight. It is prescribed for a short period with a calorie control diet and exercise program. Best results obtained with a diet program. The dose of phentermine ranges from 18.75 mg to 37.5 mg. 37.5 mg is the maximum dose of phentermine that a patient can take daily. The drug can be taken once daily before breakfast or three times a day before meals.
Ways to increase its efficiency:
Phentermine is prescribed only for a shorter period to fasten the fat loss process. Phentermine works better with a limited calorie diet and exercise. Diet should be controlled and calculated calories should be taken according to need. Phentermine works by reducing appetite which helps to take fewer calories and remains satisfied and controls unhealthy eating habits. Regular exercises are recommended to facilitate muscle mass loss and to provide strength to muscles. These lifestyle modifications enhance the efficiency of phentermine.
Expected weight loss with phentermine:
The fat loss process can be boosted with phentermine. It is recommended for patients older than 16 years for almost 12 weeks. Average weight reduction is 5% of starting body weight with the use of phentermine. After completion of therapy, it may increase up to 10%. Phentermine speeds up weight loss along with exercise and controlled diet.
Phentermine interacts with some other drugs that’s why caution is required while prescribing it. Selective serotonin reuptake inhibitors and Monoamine oxidase inhibitors are avoided to co-administer with phentermine because it causes hypertensive crisis. Arrhythmia and hypertensive crises are experienced when co-administered with other weight-reducing drugs like benzphetamine, amphetamine, and dextroamphetamine. Blood sugar level drops down if insulin or oral antidiabetic drug are used with phentermine. Phentermine reduces the effectiveness of reserpine
Antidepressants which cannot be taken with phentermine
Antidepressants are used to make the patient relax and control his anxiety and sadness. Different classes of antidepressants are used which treat different conditions. Patients while using phentermine cannot take all types of antidepressants bought online. Monoamine oxidase inhibitors (MAOIs) should not be prescribed with phentermine. Selective Serotonin Reuptake Inhibitors also interact with phentermine and causes hypertensive crisis.
Side effects of phentermine:
While using phentermine, the patient experiences different side effects including diarrhea, constipation, vomiting, dry mouth and headache. If they are mild then they will go away in a few days but in severe cases, it is recommended to visit your pharmacist or doctor
Factors that cause a headache during the use of phentermine:
Doctors recommend taking plenty of water while using phentermine to avoid dehydration. Dehydration increases the severity of the headache. Phentermine’s use may cause a headache because of stimulant action. Phentermine’s use with a highly restrictive diet or skipping meals will develop headaches due to low blood sugar levels. Patients suffering from insomnia develop a headache. This problem can be overcome by taking medicine in the morning so that its side effect subsides before night.
Ways to get rid of a headache:
In case of severe headache, it is recommended to stop using phentermine and get medical services as early as possible. After the use of phentermine for a while, most of the side effects disappear as the body becomes habitual. The most effective way to deal with headaches is to avoid all trigger factors which can cause headaches while taking phentermine such as skipping meals, taking other stimulants or less water intake.
Treatment of headache due to phentermine:
Over the counter, painkillers are used for minor headaches. Water intake and recommended dose should be strictly followed to avoid dehydration related headache issues. Consult your physician when headache persists. It needs proper diagnosis and medical care because severe headaches may have any basic medical problem. Then medicines are prescribed according to diagnosis.
Phentermine is a tablet that helps to reduce weight. This usually shows complete absorption after administration. It absorbs from the gastrointestinal tract and reaches maximum concentration in blood. The absorption rate differs for different composition of the dosage form. Absorption from hydrochloride salt is higher than absorption from the resin complex. It stays in the body till complete excretion of the drug through urine either in metabolized or unchanged form.
Role of the other factors in its removal:
Different factors like metabolism of the patient, age, height, duration of use, body fat and dose-effect its removal. Normally it leaves the body in 2 to 3 days but exercise and drinking more fluid speeds up its removal from the body.
Duration of phentermine’s stay in the blood:
After absorption in the body, it comes into the blood circulation and is expected to present in blood up to 24 hours after administration (typical dose of 37.5mg). If the dose is higher, the duration of the stay becomes longer. Phentermine shows 17.5% plasma protein binding means the remaining drug is available for action.
When does it start functioning in the human body:
Phentermine starts working in 3 to 4 hours after taking the tablet. In the case of the extended-release capsule, it is administered once in a day and in the case of tablets, it is administered 3 times a day. So it does not take it much time before it starts working in the human system.
The half-life of the Phentermine:
Half-life is the time, which is taken to metabolize half of the dosage of the drug or excrete unchanged drug in urine. The terminal half-life of phentermine is approximately 25 hours but it depends on the pH of urine. If the PH of the urine is acidic then the elimination half-life of the drug becomes 7-8 hours (pH <5)
The duration of its stay in the urine:
The route of excretion of the phentermine is mainly urine. Almost 70-80% of administered dose remains unchanged and the remaining dose gets metabolized by the liver. Phentermine can be detected in urine for 1 to 4 days which may vary depending on the dose. The detection of the presence of the drug is mostly performed by urine tests. Urine acidification affects the stay of phentermine in the urine. The half-life of phentermine decreases from 25 hours to 7-8 hours because of more acidic PH.